ObjectivesOur aim was to investigate the interactive causal effects between gut microbiota and host urate metabolism and explore the underlying mechanism using genetic methods. MethodsWe extracted summary statistics from the abundance of 211 microbiota taxa from the MiBioGen (N =18. 340). 205 microbiota metabolism pathways from the Dutch Microbiome Project (N =7738). https://jalyttlers.shop/product-category/slim-cabinet/